All the files located in /proc/sys can only be modified by root (actually 99.9% files, check with ls -l). Therefore you have to use sudo to modify those files (or your preferred way to execute commands as root).
The proper way to modify the files in /proc/sys is to use the sysctl tool. Note that yu should replace the slashes (/) with dots (.) and omit the /proc/sys/ prefix... read the fine manual.
Read the current value:
$ sysctl kernel.kptr_restrict 
kernel.kptr_restrict = 1
Modify the value:
$ sudo sysctl -w kernel.kptr_restrict=0
sysctl kernel.kptr_restrict=1
To make your modifications reboot persistent, you should edit  /etc/sysctl.conf or create a file in /etc/sysctl.d/50-mytest.conf (edit the file as root or using sudoedit), containing:
kernel.kptr_restrict=1
In which case you should execute this command to reload your configuration:
$ sysctl -p /etc/sysctl.conf
P.S. it is possible to directly write in the virtual file. https://stackoverflow.com/users/321730/cdyson37 command is quite elegant: echo 0 | sudo tee /proc/sys/kernel/kptr_restrict