I figured out a relatively simple way (yet slightly unconventional) to save my matplotlib figures. It works like this:
import libscript
import matplotlib.pyplot as plt
import numpy as np
t = np.arange(0.0, 2.0, 0.01)
s = 1 + np.sin(2*np.pi*t)
#<plot>
plt.plot(t, s)
plt.xlabel('time (s)')
plt.ylabel('voltage (mV)')
plt.title('About as simple as it gets, folks')
plt.grid(True)
plt.show()
#</plot>
save_plot(fileName='plot_01.py',obj=sys.argv[0],sel='plot',ctx=libscript.get_ctx(ctx_global=globals(),ctx_local=locals()))
with function save_plot defined like this (simple version to understand the logic):
def save_plot(fileName='',obj=None,sel='',ctx={}):
    """
    Save of matplolib plot to a stand alone python script containing all the data and configuration instructions to regenerate the interactive matplotlib figure.
    Parameters
    ----------
    fileName : [string] Path of the python script file to be created.
    obj : [object] Function or python object containing the lines of code to create and configure the plot to be saved.
    sel : [string] Name of the tag enclosing the lines of code to create and configure the plot to be saved.
    ctx : [dict] Dictionary containing the execution context. Values for variables not defined in the lines of code for the plot will be fetched from the context.
    Returns
    -------
    Return ``'done'`` once the plot has been saved to a python script file. This file contains all the input data and configuration to re-create the original interactive matplotlib figure.
    """
    import os
    import libscript
    N_indent=4
    src=libscript.get_src(obj=obj,sel=sel)
    src=libscript.prepend_ctx(src=src,ctx=ctx,debug=False)
    src='\n'.join([' '*N_indent+line for line in src.split('\n')])
    if(os.path.isfile(fileName)): os.remove(fileName)
    with open(fileName,'w') as f:
        f.write('import sys\n')
        f.write('sys.dont_write_bytecode=True\n')
        f.write('def main():\n')
        f.write(src+'\n')
        f.write('if(__name__=="__main__"):\n')
        f.write(' '*N_indent+'main()\n')
return 'done'
or defining function save_plot like this (better version using zip compression to produce lighter figure files):
def save_plot(fileName='',obj=None,sel='',ctx={}):
    import os
    import json
    import zlib
    import base64
    import libscript
    N_indent=4
    level=9#0 to 9, default: 6
    src=libscript.get_src(obj=obj,sel=sel)
    obj=libscript.load_obj(src=src,ctx=ctx,debug=False)
    bin=base64.b64encode(zlib.compress(json.dumps(obj),level))
    if(os.path.isfile(fileName)): os.remove(fileName)
    with open(fileName,'w') as f:
        f.write('import sys\n')
        f.write('sys.dont_write_bytecode=True\n')
        f.write('def main():\n')
        f.write(' '*N_indent+'import base64\n')
        f.write(' '*N_indent+'import zlib\n')
        f.write(' '*N_indent+'import json\n')
        f.write(' '*N_indent+'import libscript\n')
        f.write(' '*N_indent+'bin="'+str(bin)+'"\n')
        f.write(' '*N_indent+'obj=json.loads(zlib.decompress(base64.b64decode(bin)))\n')
        f.write(' '*N_indent+'libscript.exec_obj(obj=obj,tempfile=False)\n')
        f.write('if(__name__=="__main__"):\n')
        f.write(' '*N_indent+'main()\n')
return 'done'
This makes use a module libscript of my own, which mostly relies on modules inspect and ast. I can try to share it on Github if interest is expressed (it would first require some cleanup and me to get started with Github).
The idea behind this save_plot function and libscript module is to fetch the python instructions that create the figure (using module inspect), analyze them (using module ast) to extract all variables, functions and modules import it relies on, extract these from the execution context and serialize them as python instructions (code for variables will be like t=[0.0,2.0,0.01] ... and code for modules will be like import matplotlib.pyplot as plt ...) prepended to the figure instructions. The resulting python instructions are saved as a python script whose execution will re-build the original matplotlib figure.
As you can imagine, this works well for most (if not all) matplotlib figures.