horn-mad

Perhaps in reference to the figurative horns of a cuckold, who would be enraged at the moment of discovery.

horn-mad (comparative more horn-mad, superlative most horn-mad)

1. (obsolete) Furious; enraged.
   • 1598–1599 (first performance), William Shakespeare, “Much Adoe about Nothing”, in Mr. William Shakespeares Comedies, Histories, & Tragedies […] (First Folio), London: […] Isaac Iaggard, and Ed[ward] Blount, published 1623, →OCLC, (please specify the act number in uppercase Roman numerals, and the scene number in lowercase Roman numerals):

     If this should ever happen, thou wouldst be horn-mad.