titin

English

Etymology

From titan +‎ -in. From being a titanic (titan) protein (-in), a very large protein, the largest known prior to the discovery of PKZILLA.

Pronunciation

  • IPA(key): /ˈtaɪtɪn/
  • Audio (US):(file)
  • Rhymes: -aɪtɪn

Noun

titin (uncountable)

  1. (biochemistry) A protein important in the contraction of striated muscle tissues.
    • 2009 January 30, Armando del Rio et al., “Stretching Single Talin Rod Molecules Activates Vinculin Binding”, in Science[1]:
      In order to measure the pattern of force-dependent stretching of TR, we designed a DNA construct encoding for I27 2 -T R -I27 2 [TR flanked by two molecules of the I27 (27th immunoglobular domain of human cardiac titin), which has well-characterized mechanical properties.]

Synonyms

  • connectin
  • methionyl­threonyl...arginyl­seryl­isoleucine (scientific name)

Derived terms

  • TTN (gene encoding titin)

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