Doing this asynchronously is quite easy. It's particularly useful if you're concerned with blocking the thread (likely). Otherwise, I'd suggest Peter Lyon's answer
const fs = require('fs');
const fileName = './file.json';
const file = require(fileName);
    
file.key = "new value";
    
fs.writeFile(fileName, JSON.stringify(file), function writeJSON(err) {
  if (err) return console.log(err);
  console.log(JSON.stringify(file));
  console.log('writing to ' + fileName);
});
The caveat is that json is written to the file on one line and not prettified. ex:
{
  "key": "value"
}
will be...
{"key": "value"}
To avoid this, simply add these two extra arguments to JSON.stringify
JSON.stringify(file, null, 2)
null - represents the replacer function. (in this case we don't want to alter the process)
2 - represents the spaces to indent.