When you shift a value,
unsigned char x = ...;
int y = x << 16;
The type of x is promoted to int if unsigned char fits in an int (most systems), or to unsigned if unsigned char does not fit in an int (rare1).  As long as your int is 25 bits wide or wider, then no data will be discarded2.
Note that this is completely unrelated to the fact that 16 has type int.
/* All three are exactly equivalent */
x << 16;
x << 16u;
x << (unsigned char) 16;
Source: from n1516 (C99 draft):
§6.5.7 paragraph 3: Bitwise Shift Operators
The integer promotions are performed on each of the operands. The type of the result is
  that of the promoted left operand.
§6.3.1.1 paragraph 2: Boolean, characters, and integers
If an int can represent all values of the original type (as restricted by the width, for a
  bit-field), the value is converted to an int; otherwise, it is converted to an unsigned
  int. These are called the integer promotions.
Footnotes:
1: Some DSP chips as well as certain Cray supercomputers are known to have sizeof(char) == sizeof(int).  This simplifies design of the processor's load-store unit at the cost of additional memory consumption.
2: If your left shift is promoted to int and then overflows the int, this is undefined behavior (demons may fly out your nose).  By comparison, overflowing an unsigned is always well-defined, so bit shifts should usually be done on unsigned types.