You will want to use some sort of table-valued split function similar to this:
create FUNCTION [dbo].[Split](@String varchar(MAX), @Delimiter char(1))       
returns @temptable TABLE (items varchar(MAX))       
as       
begin      
    declare @idx int       
    declare @slice varchar(8000)       
    select @idx = 1       
        if len(@String)<1 or @String is null  return       
    while @idx!= 0       
    begin       
        set @idx = charindex(@Delimiter,@String)       
        if @idx!=0       
            set @slice = left(@String,@idx - 1)       
        else       
            set @slice = @String       
        if(len(@slice)>0)  
            insert into @temptable(Items) values(@slice)       
        set @String = right(@String,len(@String) - @idx)       
        if len(@String) = 0 break       
    end   
return 
end;
You can then use outer apply to join with yourtable:
select t1.reference,
  t1.name,
  t1.subjectstitle,
  i.items subjects
from yourtable t1
outer apply dbo.split(t1.subjects, ',') i
Giving a result like this:
| REFERENCE |                          NAME | SUBJECTSTITLE | SUBJECTS |
------------------------------------------------------------------------
|  LL9X81MT | Making and Decorating Pottery |        (null) |      F06 |
|  LL9X81MT | Making and Decorating Pottery |        (null) |      F27 |
|  LL9X81MT | Making and Decorating Pottery |        (null) |      F38 |
See SQL fiddle with Demo
If you want to do this without a split function, then you can use CTE:
;with cte (reference, name, subjectstitle, subjectitem, subjects) as
(
  select reference,
    name,
    subjectstitle,
    cast(left(subjects, charindex(',',subjects+',')-1) as varchar(50)) subjectitem,
         stuff(subjects, 1, charindex(',',subjects+','), '') subjects
  from yourtable
  union all
  select reference,
    name,
    subjectstitle,
    cast(left(subjects, charindex(',',subjects+',')-1) as varchar(50)) ,
    stuff(subjects, 1, charindex(',',subjects+','), '') subjects
  from cte
  where subjects > ''
) 
select reference, name, subjectstitle, subjectitem
from cte
See SQL Fiddle with Demo