The answer below doesn't work for window.console because console (like other browser-native environment variables) is treated specially. Any attempt to assign a value to console only "covers up" the original value; it does not replace it. You can't detect when the console value changes, but you can delete window.console to restore the original environment-supplied value.
For other values, use Object.defineProperty to define a custom setter for some global window.foobar. The setter function runs whenever window.foobar is assigned a new value:
(function() {
var actualFoobar = window.foobar;
Object.defineProperty(window, "foobar", {
set: function(newValue) {
if(newValue === null) {
alert("someone is clobbering foobar!"); // <-- breakpoint here!
}
// comment out to disallow setting window.foobar
actualFoobar = newValue;
},
get: function() { return actualFoobar; }
});
})();
Then, put a breakpoint in that setter function.
This approach will work for global variables or any object property (simply change window to the object that has the property).