Suppose this is your iframe (ifr.htm)- 
<html>
<head>
    <script type="text/javascript">
        function func() {
            window.top.window.f = function() {
                alert('iframe hack');
            }
        }
        window.onload = function() {
            alert('iframe loaded');
            func();
        };
    </script>
</head>
<body>
    this is the test iframe.
</body>
</html>
and this is your parent window-
<html>
<head>
    <script type="text/javascript">
        window.onload = function() {
            i = document.getElementById('iframe'); //remove the iframe
            i.parentNode.removeChild(i);
            window.f(); //you can still call f() method     
        };
    </script>
</head>
<body>
    this is the parent window.
            <iframe src="ifr.htm" id="iframe"></iframe>
</body>
</html>
This basically accesses the parent using top and adds a function to it. So even when the iframe is removed from the DOM, the function will still remain, as it was added to the parent.