I used the answer here to setup my query:
https://stackoverflow.com/a/1006668/211457
I'm running this query:
SELECT  * 
FROM    users 
WHERE   MBRContains(LineFromText(CONCAT( 
    '('    , 39.76784253493 + 10 / ( 111.1 / cos(RADIANS(39.76784253493)))
    , ' '
    , -75.871009379625 + 10 / 111.1
    , ','
    , 39.76784253493 - 10 / ( 111.1 / cos(RADIANS(-75.871009379625)))
    , ' '
    , -75.871009379625 - 10 / 111.1 
    , ')' ))
    ,location)
My database has these entries:
CREATE TABLE `users` (
  `id` int(11) unsigned NOT NULL AUTO_INCREMENT,
  `location` point NOT NULL,
  PRIMARY KEY (`id`),
  SPATIAL KEY `sx_place_location` (`location`)
) ENGINE=MyISAM DEFAULT CHARSET=utf8;
INSERT INTO `users` (`id`, `location`)
VALUES
    (1,X'000000000101000000E17A14AE47E1434088855AD3BCF752C0'),   
    (2,X'000000000101000000E9FF1F9EBEF752C0440008AA48E24340');
No results are returned, when I would expect the second row to be returned, since that's the values I used in the query. One thing I checked is if I switched the values of longitude and latitude, but in both cases nothing is returned. When I ran explain on the query it says "Impossible WHERE noticed after reading const tables". I'm using MySQL 5.1.39.
Since the export is in some encoding or something for being a point here's a screenshot. Ignore the extra columns.

edit: I ended up switching to Postgresql. A similar query is shorter and it works.
 
    