If you like to load the code you're working via import by putting its project directory under your PYTHONPATH, and the code depends on data files you've stored in the project directory, you can use __file__ to get the project location and retrieve the data.
I like to load everything I work on via import, but my coworkers run the scripts I give them inside their project directories from the command line. So in these scripts I use a getwd function defined as follows to get the correct location of the project files, regardless of how the script is run:
import os
def getwd():
    return os.path.dirname(__file__) if '__file__' in globals() else os.getcwd()
When I load the script via import, getwd returns the directory of the script. When my coworkers run the script from the command line inside their project directory, there is no global __file__, and getwd simply returns the current directory.