There is a shell option cdable_vars:
cdable_vars
If this is set, an argument to the cd builtin
command that is not a directory is assumed to be the name of a
variable whose value is the directory to change to.
You could add this to your .bashrc:
shopt -s cdable_vars
export myFold=$HOME/Files/Scripts/Main
Notice that I've replaced the tilde with $HOME; quotes prevent tilde expansion and Bash would complain that there is no directory ~/Files/Scripts/Main.
Now you can use this as follows:
cd myFold
No $ required. That's the whole point, actually – as shown in other answers, cd "$myFold" works without the shell option. cd myFold also works if the path in myFold contains spaces, no quoting required.
This usually even works with tab autocompletion as the _cd function in bash_completion checks if cdable_vars is set – but not every implementation does it in the same manner, so you might have to source bash_completion again in your .bashrc (or edit /etc/profile to set the shell option).
Other shells have similar options, for example Zsh (cdablevars).