After having the same question with the same issue, it would seem that the only working solution (at least to my point of view) is as followed :
PlotView.InvalidatePlot(true)
Doing so, after updating one or multple Series do refresh your PlotView.
The refresh rate depends on how often, or at which rate your serie(s) is/are updated.
Here is a code snippet (on Xamarin Android but should work anyway) :
PlotView resultsChart = FindViewById<PlotView>(Resource.Id.resultsChart);
PlotModel plotModel = new PlotModel
{
    // set here main properties such as the legend, the title, etc. example :
    Title = "My Awesome Real-Time Updated Chart",
    TitleHorizontalAlignment = TitleHorizontalAlignment.CenteredWithinPlotArea,
    LegendTitle = "I am a Legend",
    LegendOrientation = LegendOrientation.Horizontal,
    LegendPlacement = LegendPlacement.Inside,
    LegendPosition = LegendPosition.TopRight
    // there are many other properties you can set here
}
// now let's define X and Y axis for the plot model
LinearAxis xAxis = new LinearAxis();
xAxis.Position = AxisPosition.Bottom;
xAxis.Title = "Time (hours)";
LinearAxis yAxis = new LinearAxis();
yAxis.Position = AxisPosition.Left;
yAxis.Title = "Values";
plotModel.Axes.Add(xAxis);
plotModel.Axes.Add(yAxis);
// Finally let's define a LineSerie
LineSeries lineSerie = new LineSeries
 {
    StrokeThickness = 2,
    CanTrackerInterpolatePoints = false,
    Title =  "Value",
    Smooth = false
  };
plotModel.Series.Add(lineSerie);
resultsChart.Model = plotModel;
Now, whenever you need to add DataPoints to your LineSerie and to updated automatically the PlotView accordingly, just do as followed :
resultsChart.InvalidatePlot(true);
Doing so will automatically refresh your PlotView.
On a side note, the PlotView will also be updated when an event occurs such as a touch, a pinch to zoom, or any kind of UI-related events.
I hope I could help. I had trouble with this for a very long time.