Create Mutable Attributed string, do following steps
NSMutableAttributedString * attrString = [[NSMutableAttributedString alloc] initWithString:yourTextView.text];
1) Found Hello! range and set font with size
NSRange foundRange = [attrString rangeOfString:@"Hello!"];
if (foundRange.location != NSNotFound)
{
    [attrString beginEditing];
    [attrString addAttribute: NSFontAttributeName
                   value:[[UIFont boldSystemFontOfSize:17] fontName]
                   range:boldedRange];
    [attrString endEditing];
}
2) Search range for only 30 seconds and set underline style
foundRange = [attrString rangeOfString:@"only 30 seconds"];
if (foundRange.location != NSNotFound)
{
    [attrString beginEditing];
    [attrString addAttribute:NSUnderlineStyleAttributeName value:[NSNumber numberWithInt:1] range:foundRange];
    [attrString endEditing];
}
3) Search range for once! and set stroke color.
foundRange = [attrString rangeOfString:@"once!"];
if (foundRange.location != NSNotFound)
{
    [attrString beginEditing];
    [attrString addAttribute:NSStrokeColorAttributeName value:[UIColor redColor] range:foundRange];
    [attrString endEditing];
}
Finally set attributed string to your textview as
yourTextView.attributedText = attrString;
Note: The above only work with ios6+..