Here's a quote from a recent blog post from Dare Obasanjo.
SQL databases are like automatic
  transmission and NoSQL databases are
  like manual transmission. Once you
  switch to NoSQL, you become
  responsible for a lot of work that the
  system takes care of automatically in
  a relational database system. Similar
  to what happens when you pick manual
  over automatic transmission. Secondly,
  NoSQL allows you to eke more
  performance out of the system by
  eliminating a lot of integrity checks
  done by relational databases from the
  database tier. Again, this is similar
  to how you can get more performance
  out of your car by driving a manual
  transmission versus an automatic
  transmission vehicle.
However the most notable similarity is
  that just like most of us can’t really
  take advantage of the benefits of a
  manual transmission vehicle because
  the majority of our driving is sitting
  in traffic on the way to and from
  work, there is a similar harsh reality
  in that most sites aren’t at Google or
  Facebook’s scale and thus have no need
  for a Bigtable or Cassandra.
To which I can add only that switching from MySQL, where you have at least some experience, to CouchDB, where you have no experience, means you will have to deal with a whole new set of problems and learn different concepts and best practices. While by itself this is wonderful (I am playing at home with MongoDB and like it a lot), it will be a cost that you need to calculate when estimating the work for that project, and brings unknown risks while promising unknown benefits. It will be very hard to judge if you can do the project on time and with the quality you want/need to be successful, if it's based on a technology you don't know.
Now, if you have on the team an expert in the NoSQL field, then by all means take a good look at it. But without any expertise on the team, don't jump on NoSQL for a new commercial project.
Update: Just to throw some gasoline in the open fire you started, here are two interesting articles from people on the SQL camp. :-)
I Can't Wait for NoSQL to Die (original article is gone, here's a copy)
Fighting The NoSQL Mindset, Though This Isn't an anti-NoSQL Piece
Update: Well here is an interesting article about NoSQL
Making Sense of NoSQL