I'm running Mac OS 10.9.5 (Mavericks), I've followed https://docs.docker.com/installation/mac/ to install Docker. I get a timeout error message when I run Docker even though the boot2docker VM is running in the background.
nikhil@macbook ~> boot2docker status
running
nikhil@macbook ~> boot2docker ip
The VM's Host only interface IP address is: 192.168.59.103
nikhil@macbook ~> docker run hello-world
2014/11/01 01:01:31 Post https://192.168.59.103:2376/v1.15/containers/create: dial tcp 192.168.59.103:2376: i/o timeout
nikhil@macbook ~> docker search ubuntu
2014/11/01 01:02:40 Get https://192.168.59.103:2376/v1.15/images/search?term=ubuntu: dial tcp 192.168.59.103:2376: i/o timeout
I have verified that Docker is running inside the boot2docker VM and that my port is correct.
nikhil@macbook ~> boot2docker ssh
                        ##        .
                  ## ## ##       ==
               ## ## ## ##      ===
           /""""""""""""""""\___/ ===
      ~~~ {~~ ~~~~ ~~~ ~~~~ ~~ ~ /  ===- ~~~
           \______ o          __/
             \    \        __/
              \____\______/
 _                 _   ____     _            _
| |__   ___   ___ | |_|___ \ __| | ___   ___| | _____ _ __
| '_ \ / _ \ / _ \| __| __) / _` |/ _ \ / __| |/ / _ \ '__|
| |_) | (_) | (_) | |_ / __/ (_| | (_) | (__|   <  __/ |
|_.__/ \___/ \___/ \__|_____\__,_|\___/ \___|_|\_\___|_|
Boot2Docker version 1.3.1, build master : 9a31a68 - Fri Oct 31 03:14:34 UTC 2014
Docker version 1.3.1, build 4e9bbfa
docker@boot2docker:~$ sudo netstat -ntpl | grep docker
tcp        0      0 :::2376                 :::*                    LISTEN      629/docker