When perl code is compiled, globs for package variables/symbols are looked up (and created as necessary) and referenced directly from the compiled code.
So if you delete a symbol table entry $pkg::{n}, all the already compiled code that used $pkg::n, @pkg::n, etc., still use the original glob. But do/require'd code or eval STRING or symbolic references won't.
This code ends up with two *n globs; all the code compiled before the delete executes will reference the original one; all the code compiled after will reference the new one (and symbolic references will get whichever is in the symbol table at that point in runtime).
$n = 123;
delete $::{n};
eval '$n=456';
print $n;
eval 'print $n';
Another example:
$n = 123;
sub get_n { $n }
BEGIN { delete $::{n} }
$n = 456;
print get_n();
print $n;