The code works for the most part.
Whenever the interval is set to refresh the game card, the onclick functions no longer work and the variable no longer increments.
What am I missing here?
You Can comment out the line with the setInterval() to see the desired outcome. It should refresh every second keeping the variable score and incrementing whenever someone clicks on the images. Thanks!
 // var btn = document.getElementById('btn');
 //btn.addEventListener('click', UpdateTable);
 // Set the max length and Width
 var maxWidth = 4;
 var maxLength = 6;
 // Returns a random number
 function CreateRandom() {
   return Math.floor(Math.random() * 2 + 1);
 }
 //function to create an image
 function CreateGopher() {
   var randomNumber = CreateRandom();
   var image = "Sup";
   if (randomNumber == 1) {
     image = "<img src='gopher.jpg' class='gopher' height='100' width='100'>";
   } else if (randomNumber == 2) {
     image = "<img src='lettuce.jpg' class='lettuce' height='100' width='100'>";
   }
   return image;
 }
 //create table
 function UpdateTable() {
   // Iterate over each cell and set a random number
   for (var i = 0; i < maxLength; i++) {
     for (var j = 0; j < maxWidth; j++) {
       tmp = 'cell' + i + j;
       document.getElementById(tmp).innerHTML = CreateGopher();
     }
   }
 }
 function newTable() {
   // Iterate over each cell and set a random number
   for (var i = 0; i < maxLength; i++) {
     for (var j = 0; j < maxWidth; j++) {
       tmp = 'cell' + i + j;
       document.getElementById(tmp).innerHTML = CreateGopher();
     }
   }
 }
 //Use The function update table
 UpdateTable();
 setTimeout(function() {
   alert("Your Score is " + score)
 }, 15000);
 setInterval(UpdateTable, 1000);
 var score = 0;
 $(".lettuce").click(function() {
   //alert( "You Clicked on the lettuce" );
   score -= 5;
   document.getElementById("scoreOut").innerHTML = score;
 });
 $(".gopher").click(function() {
   //alert( "You Clicked on the lettuce" );
   score += 5;
   document.getElementById("scoreOut").innerHTML = score;
 });<script src="https://ajax.googleapis.com/ajax/libs/jquery/1.11.3/jquery.min.js"></script>
<center>
  <div id="container">
    <div id="header">
      <h1>Welcome</h1>
      <div id="scoreOut"></div>
    </div>
    <div id="content">
      <table id="gameCard">
        <tbody>
          <tr>
            <td id="cell00"> </td>
            <td id="cell01"> </td>
            <td id="cell02"> </td>
            <td id="cell03"> </td>
          </tr>
          <tr>
            <td id="cell10"> </td>
            <td id="cell11"> </td>
            <td id="cell12"> </td>
            <td id="cell13"> </td>
          </tr>
          <tr>
            <td id="cell20"> </td>
            <td id="cell21"> </td>
            <td id="cell22"> </td>
            <td id="cell23"> </td>
          </tr>
          <tr>
            <td id="cell30"> </td>
            <td id="cell31"> </td>
            <td id="cell32"> </td>
            <td id="cell33"> </td>
          </tr>
          <tr>
            <td id="cell40"> </td>
            <td id="cell41"> </td>
            <td id="cell42"> </td>
            <td id="cell43"> </td>
          </tr>
          <tr>
            <td id="cell50"> </td>
            <td id="cell51"> </td>
            <td id="cell52"> </td>
            <td id="cell53"> </td>
          </tr>
        </tbody>
      </table>
    </div>
  </div>
  <br>
  //<input id="btn" type="button" value="Play The Game!!" />
</center> 
    