I'm trying to make Jade work with Meteor's Flow Router and Blaze. Somehow it doesn't work for me. I'm pretty sure it's just something small that I don't notice.
HTML versions of home.jade and layout.jade files give a proper, working result.
According to this, there used to be a problem, but it was solved in 0.2.9 release of mquandalle:jade.
$ meteor list
blaze                2.1.2  Meteor Reactive Templating library
kadira:blaze-layout  2.0.0  Layout Manager for Blaze (works well with FlowRou...
kadira:flow-router   2.3.0  Carefully Designed Client Side Router for Meteor
meteor-platform      1.2.2  Include a standard set of Meteor packages in your...
mquandalle:jade      0.4.3  Jade template language
layout.jade
template(name="layout")
  +Template.dynamic(template="main")
home.jade
template(name="home")
  p Looks like working!
routes.js
FlowRouter.route('/', {
  name: 'home',
  action: function() {
    BlazeLayout.render('layout', {main: 'home'});
  }
});
The result:
<body>
  <div id="__blaze-root">
  </div>
</body>