Coming from other programming languages, String.replace() typically replaces all occurrences of matching strings. However, that is not the case with javascript/typescript. I found a number of solutions on the web with javascript utilizing regex. I immediately had issues with this solution because of special characters. I suspect there is a way to correct this with regex, but I am not a regex expert. As many have done before me, I created my own method. 
Perhaps there are ways to improve performance by making use of a custom StringBuilder() class. I welcome any thoughts.
public static Replace = function (originalString: string, oldValue: string, newValue: string, ignoreCase: boolean = false) {
    //
    // if invalid data, return the original string
    //
    if ((originalString == null) || (oldValue == null) || (newValue == null) || (oldValue.length == 0) )
        return (originalString);
    //
    // do text replacement
    //
    var dest = "";        
    var source: string = originalString;
    if (ignoreCase) 
    {
        source = source.toLocaleLowerCase();
        oldValue = oldValue.toLowerCase();
    }
    //
    // find first match
    //
    var StartPos = 0;
    var EndPos = source.indexOf(oldValue, StartPos);
    var Skip = (EndPos >= 0) ? EndPos - StartPos : source.length-StartPos;   
    //
    // while we found a matched string
    //     
    while (EndPos > -1) {
        //
        // copy original string skipped segment
        //
        if (Skip > 0) dest += originalString.substr(StartPos, Skip);            
        //
        // copy new value
        //
        dest += newValue;
        //
        // skip over old value
        //
        StartPos = EndPos + oldValue.length;
        //
        // find next match
        //
        EndPos = source.indexOf(oldValue, StartPos);
        Skip = (EndPos >= 0) ? EndPos - StartPos : source.length - StartPos;    
    }
    //
    // append the last skipped string segment from original string
    //
    if (Skip > 0) dest += originalString.substr(StartPos, Skip);   
    return dest;
}
In order to add support to this method to the string class I added the following code:
interface String { EZReplace(oldValue: string, newValue: string, ignorCase?: boolean): string; }
String.prototype.EZReplace = function (oldValue: string, newValue: string, ignorCase: boolean = false) {
return EZUtil.Replace(this, oldValue, newValue, ignorCase);}
....After re-viewing other posts, I modified the code to use regular expressions. It would be interesting to execute performance tests.
 public static Replace = function (originalString: string, oldValue: string, newValue: string, ignoreCase: boolean = false) {
    //
    // if invalid data, return the original string
    //
    if ((originalString == null) || (oldValue == null) || (newValue == null) || (oldValue.length == 0))
        return (originalString);
    //
    // set search/replace flags
    //
    var Flags: string = (ignoreCase) ? "gi" : "g";
    //
    // apply regex escape sequence on pattern (oldValue)
    //
    var pattern = oldValue.replace(/[-\[\]\/\{\}\(\)\*\+\?\.\\\^\$\|]/g, "\\$&");
    //
    // replace oldValue with newValue
    //
    var str = originalString.replace(new RegExp(pattern, Flags), newValue);
    return (str);
}
 
     
     
     
    