You need to put the image in a button, and bind the button to the command:
<Button Command="{Binding MyCommand}">
    <Image Source="myImage.png" />
</Button>
If you don't want the standard button chrome, just change the template of the button with something like that:
<ControlTemplate x:Key="tplFlatButton" TargetType="{x:Type Button}">
    <Border Width="{TemplateBinding Width}"
            Height="{TemplateBinding Height}"
            Background="{TemplateBinding Background}"
            BorderBrush="{TemplateBinding BorderBrush}"
            BorderThickness="{TemplateBinding BorderThickness}">
        <ContentPresenter HorizontalAlignment="{TemplateBinding HorizontalContentAlignment}"
                          VerticalAlignment="{TemplateBinding VerticalContentAlignment}"
                          TextElement.Foreground="{TemplateBinding Foreground}"
                          TextElement.FontFamily="{TemplateBinding FontFamily}"
                          TextElement.FontSize="{TemplateBinding FontSize}"
                          TextElement.FontStretch="{TemplateBinding FontStretch}"
                          TextElement.FontWeight="{TemplateBinding FontWeight}"/>
    </Border>
</ControlTemplate>
Note that you will also need to change other properties to override the default button style, otherwise the template above will use the default button background and border:
<Style x:Key="stlFlatButton" TargetType="{x:Type Button}">
    <Setter Property="Background" Value="{x:Null}" />
    <Setter Property="BorderBrush" Value="{x:Null}" />
    <Setter Property="BorderThickness" Value="0" />
    <Setter Property="Template" Value="{StaticResource tplFlatButton}" />
</Style>