Thought to share my helper method for those who can use it:
public static class Sql
{
    public static T Read<T>(DbDataReader DataReader, string FieldName)
    {
        int FieldIndex;
        try { FieldIndex = DataReader.GetOrdinal(FieldName); }
        catch { return default(T); }
        if (DataReader.IsDBNull(FieldIndex))
        {
            return default(T);
        }
        else
        {
            object readData = DataReader.GetValue(FieldIndex);
            if (readData is T)
            {
                return (T)readData;
            }
            else
            {
                try
                {
                    return (T)Convert.ChangeType(readData, typeof(T));
                }
                catch (InvalidCastException)
                {
                    return default(T);
                }
            }
        }
    }
}
Usage:
cmd.CommandText = @"SELECT DISTINCT [SoftwareCode00], [MachineID] 
                    FROM [CM_S01].[dbo].[INSTALLED_SOFTWARE_DATA]";
using (SqlDataReader data = cmd.ExecuteReader())
{
    while (data.Read())
    {
        usedBy.Add(
            Sql.Read<String>(data, "SoftwareCode00"), 
            Sql.Read<Int32>(data, "MachineID"));
    }
}
The helper method casts to any value you like, if it can't cast or the database value is NULL, the result will be null.