While checking null or Empty value for a column, I noticed that there are some support concerns in various Databases.
Every Database doesn't support TRIM method.
Below is the matrix just to understand the supported methods by different databases.
The TRIM function in SQL is used to remove specified prefix or suffix from a string. The most common pattern being removed is white spaces. This function is called differently in different databases:
- MySQL: TRIM(), RTRIM(), LTRIM()
- Oracle: RTRIM(), LTRIM()
- SQL Server: TRIM(), RTRIM(), LTRIM()
How to Check Empty/Null/Whitespace :- 
Below are two different ways according to different Databases-
The syntax for these trim functions are:
- Use of Trim to check-  - SELECT FirstName FROM UserDetails WHERE TRIM(LastName) IS NULL
 
- Use of LTRIM & RTRIM to check-  - SELECT FirstName FROM UserDetails WHERE LTRIM(RTRIM(LastName)) IS NULL
 
Above both ways provide same result just use based on your DataBase support. It Just returns the FirstName from UserDetails table if it has an empty LastName
Hoping this will help others too :)