I have tried to call remote validation by using below code
In component file
Validation code
this.formCompany = this.fb.group({
    varEmail: [null, Validators.compose([Validators.required, Validators.maxLength(150),this.emailExist.bind(this)])],
}});
function for check email exist or not
emailExist(control: FormControl) {
    if(control.value) {  
      this.services.emailExist(control.value).subscribe(res => {this.checkEmailExist = res;
        if(this.checkEmailExist.exist > 0) {
            return { 'emailexist': true };
        } else {
             return null;
        }
        } );
    } else {
        return null;
    }
}
HTML Code
<div fxLayout="row" fxLayoutWrap="wrap">
   <md-input-container class="ml-xs mr-xs" style="width: 60%">
      <input mdInput placeholder="Email Address" maxlength="150"  [ngModel]="CompanyEdit.varEmail" [formControl]="formCompany.controls['varEmail']">
   </md-input-container>
<small *ngIf="formCompany.controls['varEmail'].hasError('required') && formCompany.controls['varEmail'].touched" class="mat-text-warn">Please insert email address.</small>
<small *ngIf="formCompany.controls['varEmail'].hasError('maxlength') && formCompany.controls['varEmail'].touched" class="mat-text-warn">Email address can not exceed 150 characters.</small>
<small *ngIf="formCompany.controls['varEmail'].hasError('emailexist') && formCompany.controls['varEmail'].touched" class="mat-text-warn">Email address already exist.</small>
</div>
This code not working.
 
    