Exactly for GitHub, there is an example on using the Github GraphQL API with Python 3
https://gist.github.com/gbaman/b3137e18c739e0cf98539bf4ec4366ad
(check link as it has a lot of comments including better code for authentication)
# An example to get the remaining rate limit using the Github GraphQL API.
import requests
headers = {"Authorization": "Bearer YOUR API KEY"}
def run_query(query): # A simple function to use requests.post to make the API call. Note the json= section.
    request = requests.post('https://api.github.com/graphql', json={'query': query}, headers=headers)
    if request.status_code == 200:
        return request.json()
    else:
        raise Exception("Query failed to run by returning code of {}. {}".format(request.status_code, query))
        
# The GraphQL query (with a few aditional bits included) itself defined as a multi-line string.       
query = """
{
  viewer {
    login
  }
  rateLimit {
    limit
    cost
    remaining
    resetAt
  }
}
"""
result = run_query(query) # Execute the query
remaining_rate_limit = result["data"]["rateLimit"]["remaining"] # Drill down the dictionary
print("Remaining rate limit - {}".format(remaining_rate_limit))
And there are many Python GraphQL client libraries:
Official list is at https://graphql.org/code/#python
(just scroll down, client libraries are after server libraries)