Please, move this question to Code Review -area. It is better suited there because I know the code below is junk and I want critical feedback to complete rewrite. I am pretty much reinventing the wheel.
# Description: you are given a bitwise pattern and a string
# you need to find the number of times the pattern matches in the string.
# The pattern is determined by markov chain.
# For simplicity, suppose the ones and zeros as unbiased coin flipping
# that stops as it hits the pattern, below.
#
# Any one liner or simple pythonic solution?
import random
def matchIt(yourString, yourPattern):
        """find the number of times yourPattern occurs in yourString"""
        count = 0
        matchTimes = 0
        # How can you simplify the for-if structures?
        # THIS IS AN EXAMPLE HOW NOT TO DO IT, hence Code-Smell-label
        # please, read clarifications in [Update]
        for coin in yourString:
            #return to base
            if  count == len(pattern):
                    matchTimes = matchTimes + 1
                    count = 0
            #special case to return to 2, there could be more this type of conditions
            #so this type of if-conditionals are screaming for a havoc
            if count == 2 and pattern[count] == 1:
                    count = count - 1
            #the work horse
            #it could be simpler by breaking the intial string of lenght 'l'
            #to blocks of pattern-length, the number of them is 'l - len(pattern)-1'
            if coin == pattern[count]:
                    count=count+1
        average = len(yourString)/matchTimes
        return [average, matchTimes]
# Generates the list
myString =[]
for x in range(10000):
    myString= myString + [int(random.random()*2)]
pattern = [1,0,0]
result = matchIt(myString, pattern)
print("The sample had "+str(result[1])+" matches and its size was "+str(len(myString))+".\n" +
        "So it took "+str(result[0])+" steps in average.\n" +
        "RESULT: "+str([a for a in "FAILURE" if result[0] != 8]))
# Sample Output
# 
# The sample had 1656 matches and its size was 10000.
# So it took 6 steps in average.
# RESULT: ['F', 'A', 'I', 'L', 'U', 'R', 'E']
[Update]
I will explain here a bit about theory, perhaps, the problem can be simplified that way. The above code try to construct the markov chain with transition matrix A below. The pattern 100 that you can imagine as coin flipping corresponds to it. 
>>> Q=numpy.matrix('0.5 0.5 0; 0 0.5 0.5; 0 0.5 0')     
>>> I=numpy.identity(3)
>>> I
array([[ 1.,  0.,  0.],
       [ 0.,  1.,  0.],
       [ 0.,  0.,  1.]])
>>> Q
matrix([[ 0.5,  0.5,  0. ],
        [ 0. ,  0.5,  0.5],
        [ 0. ,  0.5,  0. ]])
>>> A=numpy.matrix('0.5 0.5 0 0; 0 0.5 0.5 0; 0 0.5 0 0.5; 0 0 0 1')
>>> A
matrix([[ 0.5,  0.5,  0. ,  0. ],
        [ 0. ,  0.5,  0.5,  0. ],
        [ 0. ,  0.5,  0. ,  0.5],
        [ 0. ,  0. ,  0. ,  1. ]])
The average 8 in the question becomes the sum of values on the first row in the matrix N=(I-Q)^-1 where Q above.
>>> (I-Q)**-1
matrix([[ 2.,  4.,  2.],
        [ 0.,  4.,  2.],
        [ 0.,  2.,  2.]])
>>> numpy.sum(((I-Q)**-1)[0])
8.0
Now, you can probably see that this apparently-only-pattern-matching-problem becomes a markov chain. I cannot see a reason why you could not substitute the messy for-while-if conditions with something similar to matrices or matrices. I don't know how to implement them but iterators could be a way to go, researching, particularly with more states where you need to decompose.
But a problem emerged with Numpy, what are the things -Inf and NaN for? Check the values to which they should converge, above, from (I-Q)**-1 matrix. The N is from N=I+Q+Q^2+Q^3+...=\frac{I-Q^{n}}{I-Q}.
>>> (I-Q**99)/(I-Q)
matrix([[  2.00000000e+00,   1.80853571e-09,             -Inf],
        [             NaN,   2.00000000e+00,   6.90799171e-10],
        [             NaN,   6.90799171e-10,   1.00000000e+00]])
>>> (I-Q**10)/(I-Q)
matrix([[ 1.99804688,  0.27929688,        -Inf],
        [        NaN,  1.82617188,  0.10742188],
        [        NaN,  0.10742188,  0.96679688]])
 
     
     
     
    