But ultimately I believe this problem is because the Node backend is running on a different port to the React front end.
Okay,
MERN is fantastic.
My only problem was I couldn't use Mongoose on the React side, I came across this issue and after a few hours, I found a better solution,
No need to put anything on package.json, no need to worry about CORS, 
here's a working example of a user registration using mongoose (mongoose will never run on client side, don't waste time, the library modification is time consuming),
start your express server on a port, lets say 3030, and React runs on 3000,
on React side,
constructor(){ 
...
  this.server = server || 'https://my.ip.add.ress:3030'
...
}
register(username, password, signup = true) { 
return this.fetch(`${this.server}/server/register`, {
            method: 'POST',
            headers: {
                'Accept': 'application/json',
                'Content-Type': 'application/json'
            },
            body: JSON.stringify({
                username,
                password,
                signup
            })
        }).then(res => { console.log(res);
            this.setToken(res.token) // Setting the token in localStorage
            return Promise.resolve(res);
        })
}
On Node.JS  server (express) side, 
Create a folder 'server' and create a file server.js,
var MongoNode   = require('mongoosenode')   // I created this package for just to test mongoose which doesn't run on React side, 
var cors        = require('cors');  //use cors for cross-site request
var options = {
        key     : fs.readFileSync('server.key'),
        cert    : fs.readFileSync('server.cert'),
    };
    /*
     * Cors Options
     */ 
    var whitelist = config.allowedOrigins //put https://my.ip.add.ress:3000 in the allowedOrigins array in your config file
    var corsOptions = {
        origin: function (origin, callback) {
            if (whitelist.indexOf(origin) !== -1) {
                callback(null, true)
            } else {
                callback(new Error('Not allowed by CORS'))
            }
        }
    }
    //specify the port
    var https_port = config.server.port || 3030;
    //use app or any route included to server.js
     app.post('/register', cors(corsOptions),function(req, res) {
        //Process requests
        console.log(req.body);  //see if request payload popping up
        var mn = new MongoNode('mongodb://username:password@127.0.0.1:27017/databasename')
        var user = mn.retrieveModel('User','User').then(async(res) => { 
           try { 
             user = res.model;
              console.log(user);
              user.username = req.body.username
              user.password = req.body.password
              user.token = token_str  //jwt web token to save browser cookie 
              user.save(function(err) {
                 if (err) throw err;
                 console.log('user saved successfully');
                 res.json({ success: true, token: user.token});
              });                  
           }catch(e) { 
             console.log(e);
           }
        })
        user.save(function(err) {
            if (err) throw err;
            //console.log('user saved successfully');
            res.json({ success: true , message: 'user saved successfully', token : user.token });
        });
    }
Voila! it's done easily after a few hours of reading.