I'm using the following to left align cells in a UICollectionView…
class LeftAlignedFlowLayout: UICollectionViewFlowLayout {
    override func layoutAttributesForElements(in rect: CGRect) -> [UICollectionViewLayoutAttributes]? {
        guard let attributes = super.layoutAttributesForElements(in: rect) else { return nil }
        for attributes in attributes where attributes.representedElementCategory == .cell {
            attributes.frame = layoutAttributesForItem(at: attributes.indexPath).frame
        }
        return attributes
    }
    override func layoutAttributesForItem(at indexPath: IndexPath) -> UICollectionViewLayoutAttributes {
        let currentItemAttributes = super.layoutAttributesForItem(at: indexPath)!
        let layoutWidth = collectionView!.frame.width - sectionInset.left - sectionInset.right
        // Just left align the first item in a section
        if indexPath.item == 0 {
            currentItemAttributes.frame.origin.x = sectionInset.left
            return currentItemAttributes
        }
        let previousIndexPath = IndexPath(item: indexPath.item - 1, section: indexPath.section)
        let previousItemFrame = layoutAttributesForItem(at: previousIndexPath).frame
        let currentItemFrame = currentItemAttributes.frame
        let wholeRowFrameForCurrentItem = CGRect(x: sectionInset.left, y: currentItemFrame.minY, width: layoutWidth, height: currentItemFrame.height)
        // Left align the first item on a row
        if !previousItemFrame.intersects(wholeRowFrameForCurrentItem) {
            currentItemAttributes.frame.origin.x = sectionInset.left
            return currentItemAttributes
        }
        currentItemAttributes.frame.origin.x = previousItemFrame.maxX + minimumInteritemSpacing
        return currentItemAttributes, it's 
    }
}
Building for iOS 11 gives…
But for iOS 12 gives…
In iOS 11, layoutAttributesForElements(in) is called 3 times - the final time with the correct frame sizes. In iOS 12, it's only called twice, with frames being the estimated size.
Per this answer, https://stackoverflow.com/a/52148520/123632 I've tried invalidating the flow layout using the UICollectionView subclass below (and "brute-forcing" in viewDidAppear of the containing view controller), but the result is unchanged.
class LeftAlignedCollectionView: UICollectionView {
    private var shouldInvalidateLayout = false
    override func layoutSubviews() {
        super.layoutSubviews()
        if shouldInvalidateLayout {
            collectionViewLayout.invalidateLayout()
            shouldInvalidateLayout = false
        }
    }
    override func reloadData() {
        shouldInvalidateLayout = true
        super.reloadData()
    }
}


 
     
    