drop all tables; 
or drop all tables from database;
drop all tables; 
or drop all tables from database;
 
    
     
    
    One way to do this would be to generate all the DDL statements using the metadata table
select 'DROP TABLE '||table_name||';'
  from user_tables
Run the query and copy-paste the output which would contains the statements for dropping tables
 
    
    One solution would be to DROP the user that owns the objects with the CASCADE option. 
DROP USER myuser CASCADE;
This will efficiently drop all user objects (tables, views, packages, procedures, ...). You will then need to recreate the user.
Else, if you want to limit the scope of your action to just dropping all of your tables (and associated constraints), you could write a procedure that dynamically generates and executes a series of DROP TABLE statements :
BEGIN
   FOR cur_rec IN (SELECT object_name FROM user_objects WHERE object_type = 'TABLE')
   LOOP
      BEGIN
         EXECUTE IMMEDIATE 'DROP TABLE "' || cur_rec.object_name || '" CASCADE CONSTRAINTS';
      EXCEPTION
         WHEN OTHERS THEN
            DBMS_OUTPUT.put_line ('FAILED: DROP TABLE "' || cur_rec.object_name || '"');
      END;
   END LOOP;
END;
/
