After publishing a .net Core Razor Pages project using a self-contained osx-64 profile and then trying to run it on a Macintosh I noticed that all the static files which reside in the wwwroot folder do not work. They simply return a blank page. There may be same issue when creating an pure MVC (not Razor Pages) site.
Here are the contents of the Startup.cs file:
using System;
using System.Collections.Generic;
using System.Linq;
using System.Threading.Tasks;
using Microsoft.AspNetCore.Builder;
using Microsoft.AspNetCore.Hosting;
using Microsoft.AspNetCore.Http;
using Microsoft.AspNetCore.Mvc;
using Microsoft.Extensions.Configuration;
using Microsoft.Extensions.DependencyInjection;
namespace WebApplication1
{
    public class Startup
    {
        public Startup(IConfiguration configuration)
        {
            Configuration = configuration;
        }
        public IConfiguration Configuration { get; }
        // This method gets called by the runtime. Use this method to add services to the container.
        public void ConfigureServices(IServiceCollection services)
        {
            services.Configure<CookiePolicyOptions>(options =>
            {
                // This lambda determines whether user consent for non-essential cookies is needed for a given request.
                options.CheckConsentNeeded = context => true;
                options.MinimumSameSitePolicy = SameSiteMode.None;
            });
            services.AddMvc().SetCompatibilityVersion(CompatibilityVersion.Version_2_2);
        }
        // This method gets called by the runtime. Use this method to configure the HTTP request pipeline.
        public void Configure(IApplicationBuilder app, IHostingEnvironment env)
        {
            if (env.IsDevelopment())
            {
                app.UseDeveloperExceptionPage();
            }
            else
            {
                app.UseExceptionHandler("/Error");
            }
            app.UseStaticFiles();
            app.UseCookiePolicy();
            app.UseMvc();
        }
    }
}
