I asked a question at http://social.msdn.microsoft.com/Forums/en-US/wpf/thread/5c7f5cdf-4351-4969-990f-29ce9ec84b87/ , but still lack a good explanation for a strange behavior.
Running the following XAML shows that the TextBlock in column 0 is width greater than 100 even though the column is set to width 100. I think that the strangeness may have something to do with it being wrapped in a ScrollViewer, but I don't know why. If I set a MaxWidth on the columns, it works fine, but setting Width does not.
- Why is the width of column 0 not being honored?
 - Why does the column sizing behave differently when you remove the scroll viewer?
 
I appreciate any explanation! This is a real puzzle to me.
<Window x:Class="WpfApplication2.MainWindow" xmlns="http://schemas.microsoft.com/winfx/2006/xaml/presentation"
        xmlns:x="http://schemas.microsoft.com/winfx/2006/xaml" Title="MainWindow" Width="300">
    <ScrollViewer HorizontalScrollBarVisibility="Auto" >
        <Grid>
            <Grid.RowDefinitions>
                <RowDefinition Height="Auto" />
                <RowDefinition Height="Auto" />
            </Grid.RowDefinitions>
            <Grid.ColumnDefinitions>
                <ColumnDefinition Width="100" />
                <ColumnDefinition Width="100" />
                <ColumnDefinition />
            </Grid.ColumnDefinitions>
            <TextBlock x:Name="textBlock" Text="{Binding ElementName=textBlock, Path=ActualWidth}" />
            <TextBlock Text="column 1" Grid.Column="1" />
            <TextBlock Grid.Row="1" Grid.ColumnSpan="3" Text="text here that is wider than the first two columns combined" />
        </Grid>
    </ScrollViewer>
</Window>