boost::functional has a factory template which is quite flexible: http://www.boost.org/doc/libs/1_54_0/libs/functional/factory/doc/html/index.html
My preference though is to generate wrapper classes which hide the mapping and object creation mechanism. The common scenario I encounter is the need to map different derived classes of some base class to keys, where the derived classes all have a common constructor signature available. Here is the solution I've come up with so far.
#ifndef GENERIC_FACTORY_HPP_INCLUDED
//BOOST_PP_IS_ITERATING is defined when we are iterating over this header file.
#ifndef BOOST_PP_IS_ITERATING
    //Included headers.
    #include <unordered_map>
    #include <functional>
    #include <boost/preprocessor/iteration/iterate.hpp>
    #include <boost/preprocessor/repetition.hpp>
    //The GENERIC_FACTORY_MAX_ARITY directive controls the number of factory classes which will be generated.
    #ifndef GENERIC_FACTORY_MAX_ARITY
        #define GENERIC_FACTORY_MAX_ARITY 10
    #endif
    //This macro magic generates GENERIC_FACTORY_MAX_ARITY + 1 versions of the GenericFactory class.
    //Each class generated will have a suffix of the number of parameters taken by the derived type constructors.
    #define BOOST_PP_FILENAME_1 "GenericFactory.hpp"
    #define BOOST_PP_ITERATION_LIMITS (0,GENERIC_FACTORY_MAX_ARITY)
    #include BOOST_PP_ITERATE()
    #define GENERIC_FACTORY_HPP_INCLUDED
#else
    #define N BOOST_PP_ITERATION() //This is the Nth iteration of the header file.
    #define GENERIC_FACTORY_APPEND_PLACEHOLDER(z, current, last) BOOST_PP_COMMA() BOOST_PP_CAT(std::placeholders::_, BOOST_PP_ADD(current, 1))
    //This is the class which we are generating multiple times
    template <class KeyType, class BasePointerType BOOST_PP_ENUM_TRAILING_PARAMS(N, typename T)>
    class BOOST_PP_CAT(GenericFactory_, N)
    {
        public:
            typedef BasePointerType result_type;
        public:
            virtual ~BOOST_PP_CAT(GenericFactory_, N)() {}
            //Registers a derived type against a particular key.
            template <class DerivedType>
            void Register(const KeyType& key)
            {
                m_creatorMap[key] = std::bind(&BOOST_PP_CAT(GenericFactory_, N)::CreateImpl<DerivedType>, this BOOST_PP_REPEAT(N, GENERIC_FACTORY_APPEND_PLACEHOLDER, N));
            }
            //Deregisters an existing registration.
            bool Deregister(const KeyType& key)
            {
                return (m_creatorMap.erase(key) == 1);
            }
            //Returns true if the key is registered in this factory, false otherwise.
            bool IsCreatable(const KeyType& key) const
            {
                return (m_creatorMap.count(key) != 0);
            }
            //Creates the derived type associated with key. Throws std::out_of_range if key not found.
            BasePointerType Create(const KeyType& key BOOST_PP_ENUM_TRAILING_BINARY_PARAMS(N,const T,& a)) const
            {
                return m_creatorMap.at(key)(BOOST_PP_ENUM_PARAMS(N,a));
            }
        private:
            //This method performs the creation of the derived type object on the heap.
            template <class DerivedType>
            BasePointerType CreateImpl(BOOST_PP_ENUM_BINARY_PARAMS(N,const T,& a))
            {
                BasePointerType pNewObject(new DerivedType(BOOST_PP_ENUM_PARAMS(N,a)));
                return pNewObject;
            }
        private:
            typedef std::function<BasePointerType (BOOST_PP_ENUM_BINARY_PARAMS(N,const T,& BOOST_PP_INTERCEPT))> CreatorFuncType;
            typedef std::unordered_map<KeyType, CreatorFuncType> CreatorMapType;
            CreatorMapType m_creatorMap;
    };
    #undef N
    #undef GENERIC_FACTORY_APPEND_PLACEHOLDER
#endif // defined(BOOST_PP_IS_ITERATING)
#endif // include guard
I am generally opposed to heavy macro use, but I've made an exception here. The above code generates GENERIC_FACTORY_MAX_ARITY + 1 versions of a class named GenericFactory_N, for each N between 0 and GENERIC_FACTORY_MAX_ARITY inclusive.
Using the generated class templates is easy. Suppose you want a factory to create BaseClass derived objects using a string mapping. Each of the derived objects take 3 integers as constructor parameters.
#include "GenericFactory.hpp"
typedef GenericFactory_3<std::string, std::shared_ptr<BaseClass>, int, int int> factory_type;
factory_type factory;
factory.Register<DerivedClass1>("DerivedType1");
factory.Register<DerivedClass2>("DerivedType2");
factory.Register<DerivedClass3>("DerivedType3");
factory_type::result_type someNewObject1 = factory.Create("DerivedType2", 1, 2, 3);
factory_type::result_type someNewObject2 = factory.Create("DerivedType1", 4, 5, 6);
The GenericFactory_N class destructor is virtual to allow the following.
class SomeBaseFactory : public GenericFactory_2<int, BaseType*, std::string, bool>
{
    public:
        SomeBaseFactory() : GenericFactory_2()
        {
            Register<SomeDerived1>(1);
            Register<SomeDerived2>(2);
        }
}; 
SomeBaseFactory factory;
SomeBaseFactory::result_type someObject = factory.Create(1, "Hi", true);
delete someObject;
Note that this line of the generic factory generator macro
#define BOOST_PP_FILENAME_1 "GenericFactory.hpp"
Assumes the generic factory header file is named GenericFactory.hpp