I have this method running in a .NET Core 2.X app running in Azure app service. I have a remote server that we use this method to call from button presses in our Angular website. that calls a remote device.
Angular button --> .NET Core app service in Azure --> another app service --> internet\cell connected device. We wait for the response from the device to return a status code.
If I quickly send commands [2 or 3 in a second] to this method it causes the app service to stop responding until I restart it. I read this post and added the [, HttpCompletionOption.ResponseHeadersRead).ConfigureAwait(false)]. 
However I can still freeze the entire app and require a restart from quickly sending commands to this method.
private async void SetEndPointValueAsync(string stunnelUrl, string username, string password)
{
            try
            {
                //set the user name and password
                var httpClientHandler = new HttpClientHandler()
                {
                    Credentials = new NetworkCredential(username, password)
                };
                using (var client = new HttpClient(httpClientHandler))
                {
                    using (var response = await client.GetAsync(stunnelUrl**, HttpCompletionOption.ResponseHeadersRead).ConfigureAwait(false)**)
                    {
                        if (response.IsSuccessStatusCode)
                        {
                            LogInfo(typeof(IntegrationService), stunnelUrl, LogAction.EndpointUpdate);
                        }
                        else
                        {
                            //request failed.
                            LogWarning(typeof(IntegrationService), stunnelUrl, LogAction.DeviceRequest);
                        }
                        //using (var content = response.Content)
                        //{
                        //    //do here your changes when required
                        //}
                    }
                }
            }
            catch (Exception e)
            {
                LogErrorDetailed(e, typeof(IntegrationService), stunnelUrl, LogAction.DeviceRequest);
            }
}
 
     
    