I have the same question as in the link below, but the answers where not satisfying for me.
ValidationRule ValidatesOnTargetUpdated NullReferenceException at Design Time
XAML
<TextBox x:Name="MyTextBox">
  <TextBox.Text>
    <Binding Path="MyText">
    </Binding>
  </TextBox.Text>
</TextBox>
Code-Behind
Binding binding = BindingOperations.GetBinding(MyTextBox, TextBox.TextProperty);
     binding?.ValidationRules.Add(new MyValidationRule()
      {
        ValidatesOnTargetUpdated = true
      });
It works with this section in code behind. But I am looking for a only XAML solution, because it is more intuitive and for me better maintainable. Does anybody have an idea?
