A multi-line macro is useful if you have a very complex macro which would be difficult to read if it were all on one line (although it's inadvisable to have very complex macros).
In general, you can write a multi-line define using the line-continuation character, \.  So e.g.
#define MY_MACRO    printf( \
    "I like %d types of cheese\n", \
    5 \
    )
But you cannot do that with your first example.  You cannot split tokens like that; the << left-shift operator must always be written without any separating whitespace, otherwise it would be interpreted as two less-than operators.  So maybe:
#define BIT3 (0x1 \
    << \
    3) \
    static int a;
which is now equivalent to your second example.
[Although I'm not sure how that macro would ever be useful!]