Pointing out that all of the Entity Framework < 6.0 suggestions generate some awkward SQL.  See second example for "clean" fix.
Ridiculous Workaround
// comparing against this...
Foo item = ...
return DataModel.Foos.FirstOrDefault(o =>
    o.ProductID == item.ProductID
    // ridiculous < EF 4.5 nullable comparison workaround http://stackoverflow.com/a/2541042/1037948
    && item.ProductStyleID.HasValue ? o.ProductStyleID == item.ProductStyleID : o.ProductStyleID == null
    && item.MountingID.HasValue ? o.MountingID == item.MountingID : o.MountingID == null
    && item.FrameID.HasValue ? o.FrameID == item.FrameID : o.FrameID == null
    && o.Width == w
    && o.Height == h
    );
results in SQL like:
SELECT TOP (1) [Extent1].[ID]                 AS [ID],
       [Extent1].[Name]               AS [Name],
       [Extent1].[DisplayName]        AS [DisplayName],
       [Extent1].[ProductID]          AS [ProductID],
       [Extent1].[ProductStyleID]     AS [ProductStyleID],
       [Extent1].[MountingID]         AS [MountingID],
       [Extent1].[Width]              AS [Width],
       [Extent1].[Height]             AS [Height],
       [Extent1].[FrameID]            AS [FrameID],
FROM   [dbo].[Foos] AS [Extent1]
WHERE  (CASE
  WHEN (([Extent1].[ProductID] = 1 /* @p__linq__0 */)
        AND (NULL /* @p__linq__1 */ IS NOT NULL)) THEN
    CASE
      WHEN ([Extent1].[ProductStyleID] = NULL /* @p__linq__2 */) THEN cast(1 as bit)
      WHEN ([Extent1].[ProductStyleID] <> NULL /* @p__linq__2 */) THEN cast(0 as bit)
    END
  WHEN (([Extent1].[ProductStyleID] IS NULL)
        AND (2 /* @p__linq__3 */ IS NOT NULL)) THEN
    CASE
      WHEN ([Extent1].[MountingID] = 2 /* @p__linq__4 */) THEN cast(1 as bit)
      WHEN ([Extent1].[MountingID] <> 2 /* @p__linq__4 */) THEN cast(0 as bit)
    END
  WHEN (([Extent1].[MountingID] IS NULL)
        AND (NULL /* @p__linq__5 */ IS NOT NULL)) THEN
    CASE
      WHEN ([Extent1].[FrameID] = NULL /* @p__linq__6 */) THEN cast(1 as bit)
      WHEN ([Extent1].[FrameID] <> NULL /* @p__linq__6 */) THEN cast(0 as bit)
    END
  WHEN (([Extent1].[FrameID] IS NULL)
        AND ([Extent1].[Width] = 20 /* @p__linq__7 */)
        AND ([Extent1].[Height] = 16 /* @p__linq__8 */)) THEN cast(1 as bit)
  WHEN (NOT (([Extent1].[FrameID] IS NULL)
             AND ([Extent1].[Width] = 20 /* @p__linq__7 */)
             AND ([Extent1].[Height] = 16 /* @p__linq__8 */))) THEN cast(0 as bit)
END) = 1
Outrageous Workaround
If you want to generate cleaner SQL, something like:
// outrageous < EF 4.5 nullable comparison workaround http://stackoverflow.com/a/2541042/1037948
Expression<Func<Foo, bool>> filterProductStyle, filterMounting, filterFrame;
if(item.ProductStyleID.HasValue) filterProductStyle = o => o.ProductStyleID == item.ProductStyleID;
else filterProductStyle = o => o.ProductStyleID == null;
if (item.MountingID.HasValue) filterMounting = o => o.MountingID == item.MountingID;
else filterMounting = o => o.MountingID == null;
if (item.FrameID.HasValue) filterFrame = o => o.FrameID == item.FrameID;
else filterFrame = o => o.FrameID == null;
return DataModel.Foos.Where(o =>
    o.ProductID == item.ProductID
    && o.Width == w
    && o.Height == h
    )
    // continue the outrageous workaround for proper sql
    .Where(filterProductStyle)
    .Where(filterMounting)
    .Where(filterFrame)
    .FirstOrDefault()
    ;
results in what you wanted in the first place:
SELECT TOP (1) [Extent1].[ID]                 AS [ID],
           [Extent1].[Name]               AS [Name],
           [Extent1].[DisplayName]        AS [DisplayName],
           [Extent1].[ProductID]          AS [ProductID],
           [Extent1].[ProductStyleID]     AS [ProductStyleID],
           [Extent1].[MountingID]         AS [MountingID],
           [Extent1].[Width]              AS [Width],
           [Extent1].[Height]             AS [Height],
           [Extent1].[FrameID]            AS [FrameID],
FROM   [dbo].[Foos] AS [Extent1]
WHERE  ([Extent1].[ProductID] = 1 /* @p__linq__0 */)
   AND ([Extent1].[Width] = 16 /* @p__linq__1 */)
   AND ([Extent1].[Height] = 20 /* @p__linq__2 */)
   AND ([Extent1].[ProductStyleID] IS NULL)
   AND ([Extent1].[MountingID] = 2 /* @p__linq__3 */)
   AND ([Extent1].[FrameID] IS NULL)