Q Does a base64 string always end with =?
A: No. (the word usb is base64 encoded into dXNi)
Q Why does an = get appended at the end?
A: As a short answer:
The last character (= sign) is added only as a complement (padding) in the final process of encoding a message with a special number of characters.
You will not have an = sign if your string has a multiple of 3 characters, because Base64 encoding takes each three bytes (a character=1 byte) and represents them as four printable characters in the ASCII standard.
Example:
(a) If you want to encode
ABCDEFG <=> [ABC] [DEF] [G]
Base64 deals with the first block (producing 4 characters) and the second (as they are complete). But for the third, it will add a double == in the output in order to complete the 4 needed characters. Thus, the result will be QUJD REVG Rw== (without spaces).
[ABC] => QUJD
[DEF] => REVG
[G] => Rw==
(b) If you want to encode ABCDEFGH <=> [ABC] [DEF] [GH]
similarly, it will add one = at the end of the output to get 4 characters.
The result will be QUJD REVG R0g= (without spaces).
[ABC] => QUJD
[DEF] => REVG
[GH] => R0g=