Is the time being spent in the actual function call, or in the function itself?
A virtual function call is noticeably slower than a non-virtual call, because the virtual call requires an extra dereference.  (Google for 'vtable' if you want to read all the hairy details.)  )Update: It turns out the Wikipedia article isn't bad on this.
"Noticeably" here, though, means a couple of instructions   If it's consuming a significant part of the total computation including time spent in the called function, that sounds like a marvelous place to consider unvirtualizing and inlining.
But in something close to 20 years of C++, I don't think I've ever seen that really happen.  I'd love to see the code.