You will have to make custom textInput component, something like this:
const [txt,setTxt] = useState("");
        <Pressable>
            <TextInput placeholder="Type Something..." onChangeText={(value)=>setTxt(value)}/>
                <View style={{flexDirection: 'row'}}>
                    {txt.split(" ").map((text)=><Text style={{fontWeight:text == "bold"?'bold':null}}>{text+" "}</Text>)}
                </View>
        </Pressable>
Replace text == "bold" with any value that you want to make bold.
Edit: if you want to make more than one word bold, group them in an array and update your condition like this:
const anArrayOfBoldStrings = ["bold","hello","stackoverflow"];
            <Pressable>
                <TextInput placeholder="Type Something..." onChangeText={(value)=>setTxt(value)}/>
                    <View style={{flexDirection: 'row'}}>
                        {txt.split(" ").map((text)=><Text style={{fontWeight:text == anArrayOfBoldStrings.includes(text?'bold':null}}>{text+" "}</Text>)}
                    </View>
            </Pressable>