You may want to have pytest as test runner. Configuration example follows.
Sample pytest.ini file:
[pytest]
norecursedirs=
    *.egg
    .git
    .tox
    .env
    _sass
    build
    dist
    migrations
    fabfile
    .tox
python_files =
    test_*.py
    tests.py
DJANGO_SETTINGS_MODULE=settings.dev
addopts=
   --reuse-db
   --nomigrations
   --cov=your_app
   --ignore=.tox
   --ignore=fabfile
   --ignore=scripts
   --ignore=settings
   --ignore=tmp
   --cov-report=html
   --cov-report=term
   --cov-report=annotate
Sample runtests.py file:
#!/usr/bin/env python
import os
import sys
import pytest
def main():
    os.environ.setdefault("DJANGO_SETTINGS_MODULE", "settings.dev")
    return pytest.main()
if __name__ == '__main__':
    sys.exit(main())
Sample requirements.txt file:
pytest==3.0.2
pytest-django==2.9.1
pytest-cov==2.2.1
Run the tests:
./runtests.py
Note, that effect is achieved through reuse-db and nomigrations directives.