If you just want to be able to accept any type, you can use * to allow any type:
function someFunction( xx:*, yy:*, flag:Boolean = true )
{
  if (xx is Number) {
    ...do stuff...
  } else if (xx is String) {
    ...do stuff...
  } else {
    ...do stuff...
  }
}
If you have a large number of various parameters where order is unimportant, use an options object:
function someFunction( options:Object )
{
  if (options.foo) doFoo();
  if (options.bar) doBar();
  baz = options.baz || 15;
  ...etc...
}
If you have a variable number of parameters, you can use the ... (rest) parameter:
function someFunction( ... args)
{
  switch (args.length)
  {
    case 2:
      arr = args[0];
      someBool = args[1];
      xx = arr[0];
      yy = arr[1];
      break;
    case 3:
      xx = args[0];
      yy = args[1];
      someBool = args[2];
      break;
    default:
      throw ...whatever...
  }
  ...do more stuff...
}
For cases where you need to call a common function to a number of classes, you should specify the interface common to each class:
function foo( bar:IBazable, flag:Boolean )
{
  ...do stuff...
  baz = bar.baz()
  ...do more stuff...
}