save .xlsx file writen by pandas and export as a django model

Question

I am going to have a web app that does some processing on user data and is going to give him/her back an excel file of processed data in Django.

here is my app/views.py function:

@login_required(login_url='/signin/')
def processing(request):
    ...
    # read imported file (uploaded by user) and do the process.
    # finally have 3 uf, vf, wf array.
    ...


    # save the file in "excel_file = models.FileField"
    from pandas import DataFrame, ExcelWriter
    data = {
       'uf': uf,
       'vf': vf,
       'wf': wf,
    }
    excel_data = DataFrame(excel_data)
 
    despiked = Despiking(
        #other models

        excel_file=excel_data.to_excel(???),
        )
        despiked.save()

    return render(request, 'filteration/despiking.html', context=context)

how can I save the excel_data into its model (excel_file) and create its media into Media directory?

I already have read django pandas dataframe download as excel file question, but wasn't able to fix the problem with HttpResponse. any help would be greatly appreciated