This is based on code in the Pretty and Humane date & time threads.  I added handling for "last Monday, 5pm", because I like that more than x days ago.  This handles past and future up to centuries.  I am keen on the internationalization aspect so this needs a lot more work eventually.  Calculations are in the local time zone.
public static class DateTimePretty
{
    private const int SECOND = 1;
    private const int MINUTE = 60 * SECOND;
    private const int HOUR = 60 * MINUTE;
    private const int DAY = 24 * HOUR;
    private const int WEEK = 7 * DAY;
    private const int MONTH = 30 * DAY;
    private const int YEAR = 365;
    const string now = "just now";
    const string secondsFuture = "in {0} seconds", secondsPast = "{0} seconds ago";
    const string minuteFuture = "in about a minute", minutePast = "about a minute ago";
    const string minutesFuture = "in about {0} minutes", minutesPast = "about {0} minutes ago";
    const string hourFuture = "in about an hour", hourPast = "about an hour ago";
    const string hoursFuture = "in about {0} hours", hoursPast = "about {0} hours ago";
    const string tomorrow = "tomorrow, {0}", yesterday = "yesterday, {0}";
    const string nextDay = "{0}", nextWeekDay = "next {0}", lastDay = "last {0}";
    //const string daysFuture = "in about {0} days", daysPast = "about {0} days ago";
    const string weekFuture = "in about a week", weekPast = "about a week ago";
    const string weeksFuture = "in about {0} weeks", weeksPast = "about {0} weeks ago";
    const string monthFuture = "in about a month", monthPast = "about a month ago";
    const string monthsFuture = "in about {0} months", monthsPast = "about {0} months ago";
    const string yearFuture = "in about a year", yearPast = "about a year ago";
    const string yearsFuture = "in about {0} years", yearsPast = "about {0} years ago";
    const string centuryFuture = "in about a century", centuryPast = "about a century ago";
    const string centuriesFuture = "in about {0} centuries", centuriesPast = "about {0} centuries ago";
    /// <summary>
    /// Returns a pretty version of the provided DateTime: "42 years ago", or "in 9 months".
    /// </summary>
    /// <param name="dateTime">DateTime in local time format, not Utc</param>
    /// <returns>A pretty string</returns>
    public static string GetPrettyDate(DateTime dateTime)
    {
        DateTime dateTimeNow = DateTime.Now;
        bool isFuture = (dateTimeNow.Ticks < dateTime.Ticks);
        var ts = isFuture ? new TimeSpan(dateTime.Ticks - dateTimeNow.Ticks) : new TimeSpan(dateTimeNow.Ticks - dateTime.Ticks);
        double delta = ts.TotalSeconds;
        if (delta < 10)
            return now;
        if (delta < 1 * MINUTE)
            return isFuture ? string.Format(secondsFuture, ts.Seconds) : string.Format(secondsPast, ts.Seconds);
        if (delta < 2 * MINUTE)
            return isFuture ? minuteFuture : minutePast;
        if (delta < 45 * MINUTE)
            return isFuture ? string.Format(minutesFuture, ts.Minutes) : string.Format(minutesPast, ts.Minutes);
        if (delta < 2 * HOUR)
            return isFuture ? hourFuture : hourPast;
        if (delta < 7 * DAY)
        {
            string shortTime = DateTimeFormatInfo.CurrentInfo.ShortTimePattern;
            string shortWeekdayTime = "dddd, " + shortTime;
            int dtDay = (int) dateTime.DayOfWeek;
            int nowDay = (int) dateTimeNow.DayOfWeek;
            if (isFuture)
            {
                if (dtDay == nowDay)
                {
                    if (delta < DAY)
                        return string.Format(hoursFuture, ts.Hours);
                    else
                        return string.Format(nextWeekDay, dateTime.ToString(shortWeekdayTime));
                }
                else if (dtDay - nowDay == 1 || dtDay - nowDay == -6)
                    return string.Format(tomorrow, dateTime.ToString(shortTime));
                else
                    return string.Format(nextDay, dateTime.ToString(shortWeekdayTime));
            }
            else
            {
                if (dtDay == nowDay)
                {
                    if (delta < DAY)
                        return string.Format(hoursPast, ts.Hours);
                    else
                        return string.Format(lastDay, dateTime.ToString(shortWeekdayTime));
                }
                else if (nowDay - dtDay == 1 || nowDay - dtDay == -6)
                    return string.Format(yesterday, dateTime.ToString(shortTime));
                else
                    return string.Format(lastDay, dateTime.ToString(shortWeekdayTime));
            }
        }
        //if (delta < 7 * DAY)
        //    return isFuture ? string.Format(daysFuture, ts.Days) : string.Format(daysPast, ts.Days);
        if (delta < 4 * WEEK)
        {
            int weeks = Convert.ToInt32(Math.Floor((double) ts.Days / 30));
            if (weeks <= 1)
                return isFuture ? weekFuture : weekPast;
            else
                return isFuture ? string.Format(weeksFuture, weeks) : string.Format(weeksPast, weeks);
        }
        if (delta < 12 * MONTH)
        {
            int months = Convert.ToInt32(Math.Floor((double) ts.Days / 30));
            if (months <= 1)
                return isFuture ? monthFuture : monthPast;
            else
                return isFuture ? string.Format(monthsFuture, months) : string.Format(monthsPast, months);
        }
        // Switch to days to avoid overflow
        delta = ts.TotalDays;
        if (delta < 100 * YEAR)
        {
            int years = Convert.ToInt32(Math.Floor((double) ts.TotalDays / 365.25));
            if (years <= 1)
                return isFuture ? yearFuture : yearPast;
            else
                return isFuture ? string.Format(yearsFuture, years) : string.Format(yearsPast, years);
        }
        else
        {
            int centuries = Convert.ToInt32(Math.Floor((double) ts.TotalDays / 365.2425));
            if (centuries <= 1)
                return isFuture ? centuryFuture : centuryPast;
            else
                return isFuture ? string.Format(centuriesFuture, centuries) : string.Format(centuriesPast, centuries);
        }
    }
}