In some cases slugify isn't enough standalone. I'm using a different technique for slugs. I think this will cover most scenarios.
First create a slug.py file in your app directory and copy the following codes in it.
slug.py
import re
from django.template.defaultfilters import slugify
def unique_slugify(instance, value, slug_field_name='slug', queryset=None,
                   slug_separator='-'):
    """
    Calculates and stores a unique slug of ``value`` for an instance.
    ``slug_field_name`` should be a string matching the name of the field to
    store the slug in (and the field to check against for uniqueness).
    ``queryset`` usually doesn't need to be explicitly provided - it'll default
    to using the ``.all()`` queryset from the model's default manager.
    """
    slug_field = instance._meta.get_field(slug_field_name)
    slug = getattr(instance, slug_field.attname)
    slug_len = slug_field.max_length
    # Sort out the initial slug, limiting its length if necessary.
    slug = slugify(value)
    if slug_len:
        slug = slug[:slug_len]
    slug = _slug_strip(slug, slug_separator)
    original_slug = slug
    # Create the queryset if one wasn't explicitly provided and exclude the
    # current instance from the queryset.
    if queryset is None:
        queryset = instance.__class__._default_manager.all()
    if instance.pk:
        queryset = queryset.exclude(pk=instance.pk)
    # Find a unique slug. If one matches, at '-2' to the end and try again
    # (then '-3', etc).
    next = 2
    while not slug or queryset.filter(**{slug_field_name: slug}):
        slug = original_slug
        end = '%s%s' % (slug_separator, next)
        if slug_len and len(slug) + len(end) > slug_len:
            slug = slug[:slug_len-len(end)]
            slug = _slug_strip(slug, slug_separator)
        slug = '%s%s' % (slug, end)
        next += 1
    setattr(instance, slug_field.attname, slug)
def _slug_strip(value, separator='-'):
    """
    Cleans up a slug by removing slug separator characters that occur at the
    beginning or end of a slug.
    If an alternate separator is used, it will also replace any instances of
    the default '-' separator with the new separator.
    """
    separator = separator or ''
    if separator == '-' or not separator:
        re_sep = '-'
    else:
        re_sep = '(?:-|%s)' % re.escape(separator)
    # Remove multiple instances and if an alternate separator is provided,
    # replace the default '-' separator.
    if separator != re_sep:
        value = re.sub('%s+' % re_sep, separator, value)
    # Remove separator from the beginning and end of the slug.
    if separator:
        if separator != '-':
            re_sep = re.escape(separator)
        value = re.sub(r'^%s+|%s+$' % (re_sep, re_sep), '', value)
    return value
Then in your models.py import unique_slugify from that file. Then use it in save() method.
models.py
from django.db import models
from yourapp.slug import unique_slugify # Change "yourapp" with your app name
class Test(models.Model):
    q = models.CharField(max_length=30)
    s = models.SlugField()
    def save(self, **kwargs):
        slug = '%s' % (self.q)
        unique_slugify(self, slug)
        super(Test, self).save()