The ASUS Sabertooth X58 motherboard only supports a maximum of 24gb RAM - Since this has 6 DIMM slots, you are looking at a Max of 4gb per DIMM - With that being said, the RAM you are looking to buy, 16gb HpyerX Red Fury 16gb (2x8gb) will not work -
Additionally, your Motherboard support Triple-Channel Memory - Since this is DDR3, you can use Dual-Channel Memory, but it will run in Dual-Channel mode -
If you are looking to upgrade your Memory, it is my Suggestion to look at getting 12gb, or even topping out at 24gb, especially if your main goal is to be able to run more VM's - And when searching for RAM, try and buy Triple-Channel, as this will run a bit smoother
Here is a link to the Specifications of your Motherboard:
https://www.asus.com/Motherboards/SABERTOOTH_X58/specifications/
Hopefully this help