Pressing ESC worked for me as suggested by @simlev. For me, it was a page where a blocking pop-over would be displayed in 5-10 seconds after the page was loaded. Pressing ESC effectively stopped the JavaScript on that page. This wouldn't be a replacement for extensions like NoScript, but could be handy in similar situations.
Update on 10/2020:
Given the multiple comments about how pressing ESC does not work, one should not have much hope with this method. As stated before, this worked only for a specific case; however, I guess it does not hurt to try just to see if works for you - without much expectation.