Yes, there will be issues:
As sawdust already stated in a comment, you will most likely waste power with a too large psu since it will run in a less efficient part of it's range.
As the 80plus label tests only apply at 20% rated power upward, you might end up <20% and waste more then 20% of the power in the psu.
It will not damage anything, but higher power drain is definitly an issue. Often you can get away with a not too large, high quality psu - I've operated a very thirsty Phenom (125W TDP) together with a 80W TDP Radion 4830 on a 300W powersupply without any issues. GPU manufacturers often add a margin for low quality PSUs that don't deliver their rated power (or not enough on 12V), so you don't need to add an extra margin when you buy quality.