systemic lupus erythematosus

English

Alternative forms

  • SLE (abbreviation)

Etymology

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Noun

systemic lupus erythematosus (uncountable)

  1. (pathology) A systemic autoimmune disease (or autoimmune connective tissue disease), where the immune system attacks the body's cells and tissue and causes inflammation and tissue damage.
    • 2022 March 17, Joan T. Merrill, Victoria P. Werth, Richard Furie et al., “Phase 2 Trial of Iberdomide in Systemic Lupus Erythematosus”, in The New England Journal of Medicine, volume 386, number 11, →DOI, page 1034:
      Iberdomide, a cereblon modulator promoting degradation of the transcription factors Ikaros and Aiolos, which affect leukocyte development and autoimmunity, is being evaluated for the treatment of systemic lupus erythematosus (SLE).

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