spironolactone

From spiro +‎ -one +‎ -o- +‎ lactone.

• (Received Pronunciation) IPA^(key): /ˌspʌɪ.ɹən.ə(ʊ)ˈlæk.təʊn/
• (General American) IPA^(key): /ˌspaɪ.ɹən.oʊˈlækˌtoʊn/, /spɪˌɹoʊ.nəˈlækˌtoʊn/, /ˌspɪɚ.ə.nəˈlæk.toʊn/

• Audio (US):

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• Rhymes: -æktəʊn

spironolactone (uncountable)

1. (pharmacology) A steroid drug which acts as an antimineralocorticoid (for which purpose it is used in the treatment of certain types of edema and hypertension) and an antiandrogen (for which purpose it is used as part of some types of hormone therapy, especially for transgender women).

   Synonym: spiro (slang)

• “spironolactone”, in Lexico, Dictionary.com; Oxford University Press, 2019–2022.
• “spironolactone”, in Merriam-Webster Online Dictionary, Springfield, Mass.: Merriam-Webster, 1996–present.